Our rankings are generated through the algorithmic analysis of thousands of customer reviews about products, brands, merchant customer service levels, popularity trends, and more. We use advanced technology, including AI, to help process and organize this information at scale, supporting our analysis with greater speed and consistency. The rankings reflect our opinion and should be a good starting point for shopping.
Best Mthf Supplements of 2026
Our rankings are generated through the algorithmic analysis of thousands of customer reviews about products, brands, merchant customer service levels, popularity trends, and more. We use advanced technology, including AI, to help process and organize this information at scale, supporting our analysis with greater speed and consistency. The rankings reflect our opinion and should be a good starting point for shopping.
Best Choice
1
Intelligent Labs5mg 5-MTHF Methylfolate, Quatrefolic® MTHFR Supplement, 60-Day Supply | Contributes to maternal tissue growth & blood formation. Helps reduce fatigue & supports normal immune system function.
9.8
ExceptionalOur Rating
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.
Show moreWhy we love it
Highly bioavailable and effective.
Supports energy and mental clarity.
Ideal for MTHFR gene mutation.
2
EpigeneticsFolic Acid Supplement - 5-MTHF 100ml - Vitamin B9 Methylated Folate - Vegan
14% Off9.5
ExcellentOur Rating
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.
3
Igennus Healthcare NutritionIgennus Pure Methyl Folate 400 mcg, 180 Tablets, 5-MTHF Active Folate (B9) | Clean Label, MTHFR Supplement, Lab Verified, Vegan & Suitable for Pregnancy, One-a-Day, 6 Month Supply
9.3
ExcellentOur Rating
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.
Value for Money
4
EpigeneticsFolic Acid Supplement - 5-MTHF 30ml - Vitamin B9, Methylated Folate - Vegan | Liquid Methylfolate Supplement Providing the Activated Form Of Folic Acid, Vitamin B9 - 5-MTHF - Vegan - Made In The UK
15% Off9.2
ExcellentOur Rating
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.
5
Roundway SupplementsMethylfolate Folic Acid 5mg | 5000mcg 5-MTHF Supplement for Pregnancy | 60 Capsules, 2 Month Supply | Made in The UK by Roundway Supplements
9.1
ExcellentOur Rating
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.
6
swiss bioenergeticsMethyl Folate 600µg - 90 Capsules as Quatrefolic 5-MTHF Supplement 6S-5-methyltetrahydrofolate – the 4th Generation of Folate a Highly biologically Active Form of Folic Acid/Vitamin B9 - UK Made
8.8
Very GoodOur Rating
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.
Show moreWhy we love it
High absorption rate for better efficacy.
Suitable for vegans and vegetarians.
Made with premium quality ingredients.
7
Intelligent Labs1mg 5-MTHF Methylfolate, Quatrefolic® MTHFR Supplement, 4-Month Supply
8.7
Very GoodOur Rating
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.
Show moreWhy we love it
Advanced 4th generation folate.
Supports energy and mental health.
Highly praised absorption.
8
Epigenetics5-MTHF + B12 30ml Methylfolate & Methyl - Folate & Vitamin B12 Supplement | High Strength Folic Acid B9 1000mcg + 500mcg Vitamin B12 Methylcobalamin Liquid Drops - Vegan Friendly - Made In The UK
17% Off8.5
GoodOur Rating
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.
9
Freak AthleticsFreak Athletics Folate 5mg (L-Methylfolate) - 60 Capsules, 60 Servings
8.4
GoodOur Rating
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.
10
PurolabsPurolabs Folate Supplement – High-Potency Methylfolate (5-MTHF) for Energy, Brain Function & Prenatal Health – Bioavailable & Vegan-Friendly
8.3
GoodOur Rating
Our rankings are cleverly generated from the algorithmic analysis of thousands of customer reviews about products, brands, merchant’s customer service level, popularity, trends and more. The rankings reflect our opinion and should be a good starting point for shopping.
Similar products on Amazon
Folate (L-Methylfolate 5-MTHF) 400mcg | 90 Vegan Capsules | Health Leads | Active Vitamin B9 | MTHFR Support | Prenatal & Pregnancy | Magnesium Stearate Free | Made in Wales |
ACTIVE 5-MTHF FOLATE – NOT SYNTHETIC FOLIC ACID: Provides L-Methylfolate (5-MTHF), the biologically active form of vitamin B9. Unlike folic acid, active folate does not require conversion by the body before use. Popular with customers looking specifically for active folate, including those interested in MTHFR-related nutrition
Folate (L-Methylfolate) 1000mcg | 120 Vegan Tablets | 5-MTHF (Vitamin B9) | 4 Months Supply | Active Methylated Form of Folic Acid | One-a-Day | Suitable for Pregnancy, Pure Formula | by NutriVolv
𝗔𝗱𝘃𝗮𝗻𝗰𝗲𝗱 𝗙𝗼𝗿𝗺 𝗢𝗳 𝗙𝗼𝗹𝗮𝘁𝗲 𝗙𝗼𝗿 𝗘𝗳𝗳𝗲𝗰𝘁𝗶𝘃𝗲 𝗔𝗯𝘀𝗼𝗿𝗽𝘁𝗶𝗼𝗻 - NutriVolv L-Methylfolate 1000mcg delivers the most active and bioavailable form of folate (5-MTHF), which bypasses the body's conversion process for superior absorption. Ideal for individuals with MTHFR gene variations who may struggle to metabolise standard folic acid efficiently. A trusted choice for optimised folate support.
15% OffMethyl Folate 1000ug - 120 Vegan Tablets (4 Months Supply)
HIGH STRENGTH: Each tablet delivers 1000mcg of high-strength Folic Acid (Vitamin B9)0(15% Off)
5-MTHF Methylfolate 1000mcg, 90 Capsules, 3 Month Supply, Active Folic Acid
PURE AND BIOAVAILABLE FORM OF FOLATE: Our capsules contain L-5-Methyltetrahydrofolate, the biologically active form of folate used directly by the body at the cellular level. Unlike synthetic folic acid, this form is already methylated, making it ideal for those seeking efficient absorption. A smart choice for anyone looking for clean, quality folate supplements.
Methylfolate Folic Acid 1000mcg Drops as 5-Methyltetrahydrofolate | 5-MTHF Vitamin B9 Supplement for Pregnancy | 30ml, 60 Servings, 2 Month Supply | Made in The UK by Roundway Supplements
1000mcg Bioactive Folate (5-MTHF): Each Serving delivers 1000mcg of Methylfolate, a highly bioavailable form of folate (Vitamin B9), offering effective support before and during pregnancy.
15% Off5-MTHF + B12 + B6 for Children 30ml | Methylfolate & Vitamin B12 Drops | Folic Acid & B Vitamins For Kids - Convenient Liquid Drops - Support For Growing Children - Vegan - Sugar Free - UK Made
ACTIVE METHYLFOLATE & B VITAMINS FOR KIDS – 5-MTHF, methylfolate, Methyl B12 and Vitamin B6 (P5P) in bioavailable forms. A children's vitamin supplement suitable from birth onwards, providing targeted folate, B12 and B6 nutritional support.0(15% Off)
L-Methylfolate 5-MTHF 1000mcg - 200 Vegan Tablets (6+ Months Supply)
HIGH STRENGTH: Each tablet delivers high strength 1000ug L-Methylfolate 5-MTHF as an active form of Folic Acid.
xSpan Labs Methyl Folate 600µg - 90 Capsules as Quatrefolic 5-MTHF
POTENT – xSpan Labs one capsule daily dose of 600µg Quatrefolic has high water solubility, some 100 times more than the usual calcium salt derivative. This is important because that makes it better absorbed by mucosal cells which may facilitate access to the blood and circulation
Folate (L-Methylfolate) 1000μg – 180 Vegan Tablets – L-5-MTHF Active Form of Folic Acid/Vitamin B9 - Resealable and Recyclable Pouch by Alpha01
HIGH-STRENGTH & BIOAVAILABLE FORMULA: Each tablet delivers 500% NRV of folate as Calcium L-Methylfolate (L-5-MTHF), a biologically active and highly bioavailable form of folate, superior to traditional folic acid supplements.
New: Quatrefolic® Folate - 400µg 5-MTHF - 120 Vegan Capsules - UK Made
️MAXIMUM BIOAVAILABILITY WITH QUATREFOLIC – Our premium L-Methylfolate uses advanced 400mcg Quatrefolic, the biologically active form of Vitamin B9. Unlike synthetic folic acid, this active 5-MTHF bypasses body conversion steps to ensure immediate, efficient absorption.
